Actually, it specifically said that the overdose trend is more pronounced in females.

But what's not said seems to also be relevant to the issue you raise. For instance, for suicides, I'd wager the trend is more pronounced for males. (Though they didn't call that out. So that may or may not be the case).

But whether those in poor mental health are committing suicide, or seeking escape in opioids and other drugs, the final result was clearly the same. Doesn't really matter if you're male or female.