I know this intersection. It's at the corner of State and Division, in the heart of the Rush Street neighborhood.

The likely reason there are many tickets there is that there are many bars there, and great crowds of people who have had a bit too much to drink. There are also great crowds of cops there every weekend.

Without looking at the data, I'd expect that many of the tickets are getting written in the middle of the night, when people are too inebriated, or too distracted, to read signs carefully.