EMP blast, nets, lasers, signal jamming - there are a few ideas but nothing full proof.
I've heard of multiple people just shooting then down if they trespass, so there's always guns.
I can't remember the article but I saw on HN a story where law enforcement triangulated a drone operator who was doing something criminal like smuggling. I'm sure that would be just as beneficial for deterrence if the operator knew they would be found.