You might have seen aldjemy already but I thought I might mention it https://github.com/Deepwalker/aldjemy - let's us use SQLAlchemy queries in our django code without requiring redefining the models in an SQLAlchemy manner. It's easy to put a wrapper around it to convert SQLAlchemy results back into Django model instances.

I'm exploring using Django Channels to send data to visualisation SPA's in realtime. https://channels.readthedocs.io/en/latest/