I believe things can't go well in general in any area where money comes from organized begging ("proposals", "apply for funding"), driven by reputation ("publications", "impact factor") and where the bad eggs can't even be fired ("tenure")
From personal experience, I've always felt as though the existence of "rock star" academics always gave academia a Hollywood-like feel in terms of systemic abuse and candidly bizarre and maladaptive behaviors on the part of researchers.
Or they’ve spent way too much time in. It’s like people who spend a couple of decades in a prison, they’re fully institutionalized and feel they can’t cope with the real world.
So you're never, ever gonna work with venture capitalists?
One of the few benefits of ICO: you can now raise money without having to bother with VCs. That's a nice evolution.