Not really.

http://cache.boston.com/bonzai-fba/Globe_Graphic/2008/03/29/...

http://www.lesjones.com/www/images/posts/singles2ql8.jpg

From a purely anecdotal point of view, I have lived in 8 different cities in the U.S., including San Francisco, and it by far has the least amount of available straight women (per capita) of those 8 places.