Yes, I moved to a small island off of the coast of Georgia, just north of Jacksonville, FL. Given that it has a vibrant tourism industry, I'm not sure I'd call it "rural", though it is an hour from any larger cities. It's not quite surburban either, though.

We love it here.

The "gotcha" is the need for solid internet connectivity. That's still hard to come by in truly "rural" places we looked at. Finding good schools is also a mixed bag, but that's true in urban settings as well.