My friend works for $financial_subcontractor and he told me they have an XmX of 1,46TB on their servers so that they can load the data needed for market analysis.
The response time is quite fantastic (less than a minute), but there are drawbacks: - GC takes in the order of minutes to complete - loading the data takes 90 min from spinning rust
So yeah, it's possible, but your bottleneck becomes the storage driver.