Effect of oxytocin on the core social symptoms of autism spectrum disorder | Hacker News Reader

Effect of oxytocin on the core social symptoms of autism spectrum disorder

nature.com

28 pointsyasp16 comments

Link to full paper: https://sci-hub.tw/downloads/d669/10.1038@s41380-018-0097-2....

"Based on the present findings, we cannot recommend continuous intranasal oxytocin treatment alone at the current dose and duration for treatment of the core social symptoms of high-functioning ASD in adult men, although this large-scale trial suggests oxytocin’s possibility to treat ASD repetitive behavior."

This comment ([1]) suggests that oxytocin spray is best used on autistic children, and adults are better off with transcranial magnetic stimulation.

[1] https://news.ycombinator.com/item?id=17367150

Well this study would appear to disagree with that, given that oxytoxin treatment was a failure.

This study on adults failed. The person you were replying to suggested that oxytocin might be more effective on children, and that TMS instead might be more effective for adults.

Did anyone else read scan the article and initially think it was saying Oxycontin spray instead of Oxytocin spray?

You can administer oxytocin through an inhaler?

Yes, a nasal spray is available (prescription) for breastfeeding women who find it difficult to start the flow of their milk

There's something creepy about a mother lacking enough oxytocin to nurse their own child, considering the emotions and mental state that such a thing would suggest.

Nonetheless, it's probably really common and normal, and likely serves as a vital check for the prevailing health of the population.

Which we now override by artificial means, because we can, and because the expectations for a social facade of parenting place a great degree of pressure to perform activities perceived as normal by external observers, as evidenced by my own comment.

They used a nasal spray.

The study failed its primary endpoint.

Anyone know of a good psychologist and/or neuropsychiatrist for adult ASD in the south or mid-peninsula Bay Area? In a really bad situation/state-of-mind rn... by bad, I mean yearning for rope and a bridge, or walking into traffic.

Same. You aren’t alone. For me, meditating is important but I usually just pace around instead, which could be worse. I am mentioning this incase you have something similar that you’re not doing. I don’t know any doctors in the area because I don’t live there. Sorry. I wish I did. Please be patient and deep breaths. Sorry I don’t have anythingg else to offer but I care.

I would highly recommend looking into microdosing psychedelics for improving state of mind.

Has worked wonders for those around me. One person suffering from depression and another young adult with Aspergers. In the young adult's case, they say that their anxiety basically has gone away. After several weeks, they are far more social and comfortable in their skin as well. Seems to be bringing some normalcy to their lives. Seems to be much better than cannabis for relaxing them. This individual gets anxiety attacks from cannabis.

If you are worried about the various myths about psychosis and flashbacks, read "A really good day" and the author goes into the safety aspect of it. TLDR, it's safe. What is not safe is mislabeled things.

The general regimen is usually a 3-day cycle.

day 1 - dose

day 2 - transitional day

day 3 - rest

day 4 - repeat

I have tried a more aggressive cycle and it's quite a bit much, so 3 days seems to be the better regularity. After some time going down to 1-2x/week is adequate in its effects as well.

A little bit of cryptocurrency and some googling can get one access with relatively little effort.

I started 3 weeks ago, it helps me a lot for anxiety! I love the energy and confidence it gives to me. A game changer. 1P-LSD, 10mcg Tuesday and Friday

I live in SF and can ask an ASD friend who lives in SF if he has any recommendations, if that’s accessible to you. But please, of you're feeling that badly, if there’s anyone you can call, please call them. If not, I’m happy to be an ear/shoulder.

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