Ask HN: How to stop bot onslaught on my website?

Hi! I have been looking through nginx logs for the last several days and noticed that a wide range of IP addresses, presumably bots, were hitting my site. They either scan for vulnerable endpoints (e.g. phpadmin, wordpress admin, etc..) or send POST requests to bogus URLs (POST "x1ffl\x93\xa7\xaf\xb3\x8a;h\x02\x19..."). In my understanding, these are most-likely script-kiddies launching unsophisticated "attacks" in order to hit low-hanging fruits. How can I block them?

P.S. These are nginx logs only. I used to experience high number of assaults on Port 22 and 23. I decided to change SSH's port to a higher number that is less than 1024 and have not experienced a single "attack" yet (I also use public key authentication, strong ciphers, AllowUsers, no root logins, decreased MaxStartups, but the point still stands)