Well there is little, but there is also some. There's a whole field of accelerated testing of components, by degrading various variables, e.g. increasing temperature, vibration, sounds, corrosive environment, materials, etc., and then using curves of exaggerated failure times to predict failure times under nominal conditions. (after making tons of models and analysis)

You can also improve your simulation (here the sky is the limit).

It really depends on the cost of mishaps and design failures, if it's high enough you can almost always improve design with additional expenditure.