AHK is good for hotkeys and keyboard/mouse overrides. And maybe some mini window automation.

If the logic grows and automation becomes complex, AutoIt is more suitable.

So far, I've used it to connect with remote mySQL/mariaDb and SQLite. In my opinion its pretty reliable, a lot than Sikuli.

ahk was forked from the last open source version of autoit. I like ahk. Never needed to use autoit.