If I'm being super honest, I never would have started my first company (A Funded Startup, that had very significant revenue for 3-4 years) if I didn't have IBS.

Once the company grew to the size that we needed a real office, my need to exit was at least partially influenced by IBS as well.

I could have gotten a job in a lot of different places, but I couldn't handle the workplace environment because I needed to use the restroom more than 10 times per day. I also had accidents where I would need to change my pants at least once a week, and always carried spare clothes in my backpack. I still keep that habit, even though I've largely conquered the disease. It's a weird PSD I kind of have.

Even today, I'd probably accept a 20% pay reduction for if a company would give me a private restroom connected to my office.