I run my own internet based business teaching full stack dev out of a bedroom converted to an office. My 2 daughters (5 & 8) are homeschooled.
It can be extremely challenging at times trying to work, but I am able to be in their life a lot more than your average dad.
I flew out to Cali to record a course last year and it was my first time away from my family for a few days. Before leaving, I thought it was going to be awesome to take a break from them. I realized just how damn attached I was to them during that time. I never experienced home sickness like that before. I was like a little baby.