We are already using Clojure and I would love to introduce Datomic as well but being a commercial database makes it pretty difficult.
This new setup is sounds cool but I would love something like that on a Kubernetes stack. In the real world Amazon is a no-go in so many situation.
I must say I often found the setup needlessly complicated. There is not much application for making setup and development easy when outside of AWS. No official way to set up of the whole stack with Docker or Kubernetes for example.