It affects folks in the same way learning that a lot of folks on Reddit/HN like to Haskell. "Oh hey I didn't know Haskell was so popular"
I post on HN with my real name, but you use a pseudonym. Nevertheless, your pseudonym has a posting history and karma number attached to it, so anything you post will "stick with you" in a persistent manner. Discussions somewhat resemble real-life discussion because one can track who's saying what, what everyone's said in the past, and so forth. If I flame you, my post probably gets deleted and I might even get banned, because that's how this community has decided to moderate itself.
Anonymous imageboards like 4chan are wholly different beasts altogether. If I post something foolish here on HN, perhaps talking out of my ass, saying something incorrect, I'd get downvotes and comments telling me why I'm wrong. You might even remember my handle as "that one guy who said the dumb incorrect thing one time" next time you see it. on 4chan, when you make a dumb post and everyone dogpiles on you, calling you out for your idiocy and calling you bad names, you can just close the tab and move on in your life. People aren't attacking YOU, they're attacking Post #418317258, and its author has closed the tab and permanently disassociated himself from it.
Everyone has to go to school, the park, etc, and I pay the same tax so having an environment that is pleasant for everyone is a required property. I can't ignore someone shouting to me insulting slurs for who I am. But no one has to go to 4chan, if someone feels offended they can just not visit it.
I would quote "Shit my dad says" on this: "Don't focus on the one guy who hates you. You don't go to the park and set your picnic down next to the only pile of dog shit."