At that scale, they would have to abandon traditional oral parliamentary procedures and switch to a text-based threaded comment medium. Reddit and HN show that it's at least possible to have hundreds and occasionally thousands of people "talking at once" without collapsing into chaos.
By comparison, I think most of us have had the experience of being in a conversation with a small group of people (or even one other person) and wanting to say something but not being given an opportunity to do so without seeming rude.
This could have other advantages as well. No reason why any one bill should block any other bill; anything with N/2+1 upvotes is passed by the House. It would also be possible for representatives to remain in their home districts among their constituents.