The answer to “How do you handle...” is that you get your shit together. Separation of duties, build and configuration standards, no customer data on random laptops.
When I was in high school, I worked at a sandwich/coffee shop. The precious commodity in that store was cash. We didn’t leave cash on a counter, or on a roll in our pockets it was in a locked register. When there was more than $500, we withdrew down to $250 and put the cash in a safe. At the end of the night, we put the cash in a locked pouch and two of us walked to the bank and put it in a dropbox.
Data is no different, just more complex.