Just stop using emacs, people. It's literally damaging you!
-vim user
Good thing being that Emacs is powerful enough to completely change itself without much effort.
I did exactly this but was always too afraid to admit it publicly, because of Emacs 'purism' users.
I love Emacs exactly because of how highly customizable everything is (without other editors bloat) but equally because I can leverage the huge user-base to not spend an infinity amount of time on customizing.
Although I appreciate other people's experience may be different with vi/vim/emacs, in my personal case I don't have to remote into other machines so I can get away with a custom init.el on my machine.
I use god-mode but found that capitalizing letters using the shift key was the biggest cause of pain for me. I retrained my left hand to use the ring finger for shift and added a post-command-hook to turn ",x" into "X", and the problem is largely gone. I also make a point to swap _ and - and also ; and : in certain modes (ahem Python) . My right pinky is still too active (RET and punctuation, but I rarely get any pain, even with a tiny laptop keyboard