Take scientific realism for example. Roughly, whether our theories have a 1-1 mapping to reality. Are the entities described by, say physics, really exist? Say an electron? Or is it just a concept or a tool we use to understand the world?
A common objection to scientific realism is Pessimistic Meta Induction. Roughly, we've been always wrong about physics and physical entities, even when we made progress, therefore we're likely wrong now (maybe less wrong but still wrong).
I personally find Structural Realism to be a compelling argument -- it's sort of a "third way". Roughly, look, we've been wrong and theories change and evolve but the basic structure of our theories remains intact. Therefore the structure must map on to reality. Full discussion here https://plato.stanford.edu/entries/structural-realism/
That's merely one example of meta questions about physics that physics itself cannot fully answer and only philosophy can help us understand. I think part of the reason we don't have consesus on the interpretation of quantum mechanics is because of this dismissal of philosophy by physicists.