Indeed, there's a reason large multi-nationals use companies like MarkMonitor as their Domain Register, even if they could get the same for $30/year, the potential loss in revenue and brand damage could be worth tens of thousands.

It is a much harder balancing act for a startup, finding a domain register who is reputable and responsive but not "overly" expensive. Even if your entire business relies on it, $1K+/year just may not be in the cards even knowing the risks.

I haven't used it but Google Domains claims they have telephone support and are reasonably priced. Might be worth people checking out, their Gsuite support has been pretty good.