I work from home 1-3 days a week. I'm also father of 3 boys (2, 8, 10) and wife is working full-time.

My only setup is my ThinkPad T450s. That's all.

At some point in my carrier I used 4 monitors, specific low profile keyboards and mice at the office but I don't miss that. It took some time (years!) to adjust my workflow to a single screen and maybe I'm not as productive as I could be but I'm still among the most productive employees at my company.

What I achieved is that I'm equally productive and +/- comfortable anywhere: at work, on the couch or office room at home, on a train, at airport, in the garden, anywhere. That consistency is more important to me than maximum efficiency.

So that and I choose what kind of tasks I work on when I'm alone or when family is at home because you can't expect to fully isolate yourself.