As of now, I changed chrome setting to disable sound on all websites. But it's a pain to unmute the tab every time I want to listen to something on a trusted website (youtube, ted, etc)
Any site says to me to stop my ad-blocker ... also black listed ... I don't need their online garbage ... I am already paying money to access their online crap!
For Youtube channel's home forced video auto-play ... I skip it ... and usually I move directly to the channel's videos listing page bypassing the channel's home page!
I HATE forcing videos or stupid content or large images on users! and I consider it "Online Abuse" and disrespect to the visiting users!
Also not only I use Ad-block ... I use uBlock https://github.com/gorhill/uBlock with "Block media elements larger than" 100KB !!
If anyone knows how to block Youtube Channel's Home video autoplay please tell me how, maybe uMatrix will help https://github.com/gorhill/uMatrix ... I didn't try uMatrix, will try it soon!
There's also dedicated anti-autoplay extensions, and you could always use a blocker add-on and not use it with any pre-made adblock lists.