It was always destined to go towards its past glory once Germany reunited. The only question was: "how long will it take for that to happen?".
1. It's not just hipsters this is affecting
2. This is not necessarily a move towards "glory". Most Berliners value the arts and cultural scene that exists in part due to low rents/cost of living and readily available performance/exhibition spaces. To see Berlin turned into another Silicon Valley would for most of us here be a major downgrade
Based on the geostrategic importance of Berlin (capital of Germany, the biggest city in Germany, central position in the EU, etc.) it should be an Alpha+ city, if not an Alpha++ city. Right now it's not due to a historical accident that is being "fixed": the separation into West and East.
According to that study from 2004 (ancient, I agree), Berlin was classified as Beta. For comparison, they classified Bucharest as Beta+. I'm Romanian, but there's no way that makes any sense unless Berlin is "underperforming".
So if you're a Berliner, brace yourself! Want it or not, Berlin will move up in the world to its rightful place and prices will go up accordingly.
The fact that "Luxembourg" - a glorified village is an "Alpha" city says more about it's significance in the European Union than any amenities/industry/jobs/lifestyle that exist (or rather don't exist) in the city.
It is however very central for Europe, and is fairly well placed for growth in the eastern EU.
Source: am from Leipzig.