My response to all things Kurzweil has always been barely interested dismissal.
However, a few years ago I read an in-depth piece, with interview, wherein he pinned almost all of his motivation on his early, traumatic experience of his own (beloved) fathers death.
Now my response is a very deep sadness for him. What he wants is so simple and easiy achievable - to have a child of his own.
Literal immortality (at the species layer, not the (cancerous) individual layer) was there for him all along - and it included all of the love and care and devotion that he has spent his lifetime mourning.
Heck, we can't even replace most organs and essentially transhumanism boils down to a brain replacement. If we can't make a spleen or a liver, we aren't making brains.
However, and this is why I side with GP, Kurzweils predictions are all veeeery conveniently made such that he himself will escape death, because he is absolutely obsessed and terrified by death, so I think he's succumbing to wishful thinking. He likes to publish future predictions, and his track record over the last decades is pretty meh.