Yes, I've run into this many times as well. Personally I'd love to get into some type of programming job (esp. at a startup), but I didn't major in CS or Computer Engineering nor have I had any professional experience in the field (read: haven't had a job programming professionally, therefore not qualified for a senior position). Maybe it's just the current economic climate but I've found this true of many startups as well (looking on job boards like Startuply, for instance).