Sorry, I thought it was generally accepted that Python's relationship with the GUI was troubled?

Put in plain English it is like this. I write quite a lot of code that integrates various enterprise systems together. Things like EDI management, and 'brokers' between incompatible API's. It is usually a mixture of Python/Bash/SQL. It is not my full-time job to code, but I get things done. As complexity increased I learned about version-control, OOP, and unit-testing. I have some pretty complex stuff in production. So I can self-learn all of those things, but not Python GUI programming

The kind of thing I would happily launch from the command line, often needs a GUI when end users are involved. Even to have an app that takes an input>click OK>do some API stuff>return an answer seems absurdly complicated in Python and [insert whichever GUI framework]. In fact I find it simpler to add a web front end and a server than I do a desktop GUI. Qt was never on my list as I have enough battles to handle without negotiation with bosses for PyQt licensing costs. Hence my interest in this development.

I didn't have this trouble with VB6 or VB.NET. Draw a box>draw a button>double-click the button>add the code you want to run when the button is clicked.

When I do the same in Python I have dozens of lines of set-up code. I have a window with a text box and a button, surely that should be three lines of code (like in html)? Then I find that things are not running in the order I expected... Imagine for instance I want to put an alert box up that says "working", then call the function to do the work, then take the alert box away when the function exits...My Python head says this should look like this

  def on_ok_clicked(event):
      alert=framework.alertbox(text="working...")
      do_important_blocking_stuff()
      alert.destroy()

and instead I find the GUI hanging while the function is running, then the alert box flash up and exit, or something equally unintuitive.

There doesn't seem to be a Pythonic or indeed simple way to handle these super straight-forward use cases. I have no aspiration to be a UX person, or learn a new paradigm just to have a button that says "GO!". I'm guessing from the other comments that Qt for Python is not going to be my savior.