It's not hard to imagine 100GbE being used inside datacenters. AFAIK, 40GbE top of rack switch is pretty common.
http://www.silicom-usa.com/pr/server-adapters/networking-ada...
I don't have anything this serious in my own production use, but I'm thinking of machines like dual socket x 32-core per socket xeons, or amd epyc, with 512GB to 1TB of RAM.
then pass vlan tagged traffic off one switch port, to each specific guest VM, of which there might be dozens to 100+ VMs, as subinterfaces of that.