I need a HackerNews Filter

I'm a regular reader of HackerNews (mainly via Twitter ATM) for startups, technology, and investment stuff. It's a great resource for me, but I waste a lot of time skimming past content that I'm just not interested in; recent examples being "Science vs Religion", "5 misconceptions about prostitution", or any stories about how "X makes us stupid".

Does anyone have a good method for filtering HackerNews? Kudos to anyone who can suggest a good solution.