Nuitka: A Python Compiler
nuitka.net
nuitka.net
The big win with a smart Python compiler is detecting when you don't need to represent data with the general "CObject" type and can use machine integer or floats. Then arithmetic becomes much faster. PyPy does some of that.
Being able to make an executable with no dependencies is worth something. It makes deployment easier. No need to fuss with containers or installing the right libraries on the target.