Take the recent Tomb Raider movie, after I've seen the trailer I had no desire at all to go watch it. Why would I watch something that I've experienced for over 20 hours in depth and on my own pace already. I don't know, maybe a lot of people got excited when they saw her with the plane: "Hey, look, it's exactly like the game!" For me it was just boring.
Instead focus on a character that isn't the main one in video games, use the setting etc. F.e. as a Dark Souls fan I would love for a movie to add some backstory for Solaire. Scrap any stupid references to the game like putting a white sign on the ground to summon somebody, instead just let Solaire meet another traveller (at a bonfire ;D) or anybody dying and then respawning. There you have it: (A already beloved character, ) a man of faith looking for divinity (or whatever) while travelling to faraway lands (supernatural or not) is confronted with the unbearable evils of this world to have a crisis of faith which he either overcomes or goes mad over.