Wading into social indicators is a tricky business without the full context of a place, so I will speak only about SV - great climate, progressive policies like enthusiastic adoption of Obamacare, unemployment benefits, good employers provide health/401k/parental leave benefits, non-racist environment (though certainly classist) etc.
Finally, my point was about "a software engineer in SV working at MAFANG or unicorns", who should not have to constantly uproot. A new job should be across the street for such a person.
[1] https://en.wikipedia.org/wiki/List_of_countries_by_suicide_r...