A plane is much easier to navigate because there aren't things like lane-dividers floating about. That's handy, but alas it does not apply to driving a car.
Just because an in-air navigation aid that allows for essentially pilot-free navigation deserving of the name "autopilot" happens to be relatively trivial to build, does not mean any navigation aid of similar complexity for other modes of transport should be called autopilot simply because they're at least as complex. If you're not automatically piloting, the name autopilot is pretty disingenuous, is it not?
Also, planes have a bunch of other navigation aids, including collision avoidance systems and ground-based air traffic control, and pretty obvious stuff like predictable flight paths and huge safety margins between nearby aircraft. An autopilot for an airplane works in that context. I kind of doubt it would work if there were thousands of planes nearby, many of which are on paths separated by distances the vehicles in question cover in tiny fractions of a second, and some of which follow almost invisible rather unpredictable paths (that drunk guy without lights over there...). Context matters.