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My source is Frys having giant signs saying final sale on all of their GPUs.

I've read that GPUs are not designed to be run 24/7 e.g. bitcoin mining.

They’re not designed to run 24/7 but they don’t have an issue with it. The GPU and the card itself have no issues running continuously.

The biggest problems come from the fans running continuously and getting worn down, and the coolers are by far the easiest part to replace.