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You might also want to go through the "HOW TO: Secure and Optimize your VPS" tutorial at WebHostingTalk: http://www.webhostingtalk.com/showthread.php?t=468168

You need to learn a lot more about DDoS if you think you can just hook up prolexic and be protected from DDoS.

Figure out your economics or bring on someone who has been there before.

try doing a search for DDoS in the colo forum over at webhostingtalk.com

Ask YC: DDoS protection