"The point is definitely not about prepared presentation" - to me this doesn't ring true at all, but I am sure it depends on the person who is getting interviewed. When I'm asked about times I've argued with my manager nothing really stands out but I'm sure that's not an acceptable answer either. Of course there are disagreements but they have never resolved to any serious argument or escalated to involving HR and even if they had I think it would be prudent to avoid talking about them. So I end up having to make up BS about something but now I'm the territory of exaggerating some minor disagreement and what I learned from it and it ends up sounding insincere. So the only way to avoid it is to prepare something for a lot of situations and to some extent rehearse before the interview. I've never had any significant interpersonal issues and I've been in the industry for six years. Most of the questions just leave me in a confused mumbling state as to me they sound a little ridiculous but at the same time I'm not allowed to just say, "no I've never had that as a problem".