Then there are interfaces like this:
* http://www.musictech.net/wp-content/uploads/2016/07/Caption-...
Things used by creative people often don't have existing widgets toolkits to draw from and entire new UIs have to be created.
Domain knowledge can be acquired along the way. Not just for games, but in general you never want to be "Just a programmer". You want to be "X that can program" or a "a programmer that knows X". You need enough domain knowledge to be useful to experts.
For cars, I don't didn't mean the car's UI itself but rather that industrial manufacturing uses tons of software with large graphics components. Things like SolidWorks or other kinds of things that analyze the physical shapes of things have a lot of just straight hardcore programming in them.
Edit: as for education, go get some! MIT open courseware has tons of calculus and engineering classes for free. The text books can be found online often times for a few bucks. The digital signal processing course was actually fun.