We absolutely should extrapolate something from those statistics.
Let's assume that the chance of killing in any two intervals of of the same number of miles traveled is the same. Let's say that the threshold for self driving cars being "good enough" is the same death rate as human drivers.
If we assume Uber is good enough, then they should kill people at a rate of at most 1.25/100,000,000. The waiting time until they first kill someone should fit an exponential distribution. The probability that a death would occur in the first t miles is 1 - e^(-lambda t) where lambda is the rate of killing people, is 1.25/100,000,000. I.e. 1 - e^( -(1.25 / 100,000,000) x 4), which is 5 x 10^-8.
If Uber has only a 5 x 10^-8 probability of driving "safely enough" they should lose their license at the very least.
Edit: Oops, 4 != 4,000,000. It should be 1 - e^( -(1.25 / 100,000,000) x 4,000,000) which is about 0.049...
Still, I think we can ask for better than a 5% chance of being the same as a human driver.
(also replaced stars with 'x' because HN was making things italic)