Rather unlikely. The namespaces are pretty easy to understand conceptually, and their interface is pretty minimal. Same goes for Quicklisp, very easy to start with, practically one function call needed in most cases.
Now there's ASDF. I know, it's a thing of beauty, but it's not simple to use or to understand.
Well, it's actually that way for good reasons: the problem it solves is complex and hard. The only comparable system I know of is Erlang releases mechanism, which is also a solid tool, but definitely not the simplest one in Erlang repertoire.
Anyway, if someone cites ASDF as a reason for struggling with Common Lisp, I find it very believable.