Hacker News Reader

Comment by snarfy | Hacker News Reader

Caffeine and cannabis work together.

> However, the combination of cannabis and caffeine mostly caused synergetic response in the level of the neurotransmitters; this implies that both substances produced their individual effects and did not cancel out the effects of one another. This is also expected since they bind primarily to various receptors. Thus, the resultant relative hyper increase is the cumulative effect of their individual influences.

View on HN

Colloquially known as a hippie speedball.

I rarely enjoy this during the work week, but it is definitely a Sunday morning staple. Great for steady mellow productivity.

Two quite different drugs don't entirely cancel out? An extraordinary finding indeed. We need to do more research.

I remember reading a lot about it canceling each other, this is pretty important.

Never heard about it, been smoking for 10+ years.

Same. To comment further: I still really enjoy my coffee.

Been smoking for a long time and a massive coffee drinker to the point work thinks something's wrong with me and Ive never felt the effects some of my googling describes regardless of my then Cannabis and Caffine intake.

> Caffeine and cannabis work together.

I wonder if it is a more extreme version of drinking tea? Tea has a calming chemical (Theanine), and caffeine so you end up with more of a mellow energy instead of the hyper energy from coffee.

Theanine is also a fairly common substance in the smartdrugs community. People often stack it with caffeine to improve concentration and supress the jumpiness that caffeine often causes in higher doses.

Reply on news.ycombinator.com