How many different early-90s display adapters, audio adapters, and such does it emulate? It also means that you'd have to source the OS and drivers. If the goal is to run old DOS games, Dosbox is generally more convenient.
I'm not sure how Qemu would emulate a NUMA arch on a non-NUMA machine.
It doesn't even attempt to emulate different memory models WRT where you need barriers AFAIK.
You can
Use -smp 8 -numa node,nodeid=0 -numa node,nodeid=1
All that does is lie to the guest over firmware (device tree, ACPI, etc.). All of the memory accesses are still uniform as far as CPU emulation is concerned.