Yes persistence pays, but however unpopular it might be around here, we are nearly all one or two rolls from disaster - be that business failure, major illness, or whatever, that can easily escalate into life ruining proportions.
I am far less inclined to simply spout "work hard and make your own luck" now than I would certainly have done in my 20s. Thirty more years of experiencing life, and seeing what sheer luck, good and bad, has done to friends, family and their businesses has changed my perspective on luck quite dramatically.
You need hard work and luck.