* Cell Phone: Make me drop everything and talk to you
* Desk Phone: If I'm free, I'll talk to you
* IM, SMS: Maybe I'm jammed and I can't reply right this second, but I'll take a look and get back ASAP. For what it's worth, Bloomberg messaging falls into this category.
* Email: Give me a couple hours and I'll write a thoughtful response
* Physical letters: Probably something important that you need to keep a hardcopy of. Expect a response in a couple days.
Email has a very nice niche that's as much a consequence of social convention as it is of the protocol. If email became realtime and people expected responses within 30 seconds or even 5 minutes, it would lose much of its value.