I've recently been asked about my choice of language to implement a new backend for some software. Imo, you want two languages + JS for the frontend if you do client-site frontend.
You want a simple, expressive language, like python with django, or ruby with rails or sinatra. You want to implement most of your application in this language, because these languages allow programmers to be very, very productive. Put in a dumb way - 10 to 20 lines of ruby with modern libraries go a really long way without golfing.
And if you notice you need performance and low latency, switch to your second language, java or go or something like that. This should be very little code, so you can throw all the really ugly optimizations at it to make it go fast. I've pushed some java services to sub-millisecond response times, but the things you gotta do with netty and lock-free data structures aren't suitable for a general audience anymore.
And I guess, on top of that you need some kinda request routing, but that's simple to do with nginx/haproxy or some kind of DNS / service discovery provided by an orchestration system.