Some autorouters have options to only use 45 or 90 degree traces where possible (in fact some of the examples in the link show this behaviour). In a similar vein, I'd like to see an autorouter that also cares about ground plane impedance and continuity: attempting to avoid ground plane islands or regions where clearances prevent ground planes from separating tracks, and even trying to keep ground planes associated with tracks in certain classes (e.g. high speed vs power lines) separated, joining only at the external power supply jack.
But, given the autorouting problem's NP hardness, especially when there are extra constraints like above, I expect that manual routing for anything beyond trivial layouts will continue to be the norm.