On one hand you have the complex licensing thing (PyQt) where you are limited to desktop of Mac, Win, Linux. On the other you have a skill (JS dev) that is good for literally any screen, on any platform with almost zero complications for commercial apps. It is a no brainer.
If it isn't obvious, I have begun the transition to embrace JS for what it is... I am learning it and it hasn't been too bad. Python will be relegated to ML/AI and glue...