If that macroscopic system (a galaxy that might have a catastrophe triggered or not) is causally connected to us, then it's destiny doesn't depend on the measurement, because it's state have already been "decohered" with us. (That is; the information about the other photon has already indirectly entangled with us.) If it isn't, then it's still entangled, and it indeed does depend on the measurement – it's a Schrödinger's galaxy.
How do you know it? I'm not aware of any proof of this statement.
Edit: of course you can, but only in the formal systems sense, which is relativel trivial.
What we think of as “proof” in physics is a combination of “this belief creates predictable experiences” and “this abstraction of belief is logically consistent.”
The first part is subjective - our beliefs about physics create predictable experiences for us, but we have no idea how large the entire domain of possible experiences is.
The second part is a tar pit full of bones, haunted by undefinability theorems.
https://en.m.wikipedia.org/wiki/Tarski%27s_undefinability_th...
So any suggestion that physics efficiently reveals the secret mechanisms of the universe is a conceit. Physics reveals what we’re able to deduce about the universe given the biases built into our experience of sentience.
When weird things fall out of quantum theory, this makes it hard to know if the weirdness is truly out there, or if it’s an artifact of our limited sentience.
However, I have the premise here that sentient systems are fundamentally similar to non-sentient systems. That is, there isn't any "special sauce" – such as soul or midi-chlorians – that causes sentient systems behave differently on micro-physical level. Instead, sentience is an emergent property, that shouldn't have effect in "low-level" details of how the universe works. This comes basically back to Occam's razor, like the other comment said.
Well, this is a big claim. In fact, no one knows. My premise is that there is special sauce, but we know nothing about it at the moment. In any case, it's just my word against your word :)
What I am saying is that if a phenomenon is explainable with less "special casing", we should buy into that explanation rather than a more complicated one. Quantum physics is explainable without the concept of sentience; it's just ABC's of philosophy of science that we shouldn't try to include anything more into our theory than is needed.
This means that once you have macroscopic interaction, the entanglement basically starts to spread at the speed of light, i.e. it'll quickly spread to humans.
Once you are entangled with something, you can no longer observe the effects of that entanglement (you are no longer an external observer), and it looks as if the entanglement was destroyed.