I'm sorry, but I don't feel the tone of the letter represents how any compromise or progress can occur. If you are completely banned from associating in any way, shape, or form with someone who espouses views different from you, because of an accusation that by so doing you are tacitly endorsing those views, puts every single person and issue at an impasse.
If you ever want to affect change, you have to talk to and interact with people you don't agree with.
There may be other issues at play here, but accusing someone of endorsing all of the viewpoints of an administration when said person has expressly disavowed those viewpoints shouldn't be ignored. Bill Nye is trying to move forward one point (promoting NASA and space exploration), and I don't think he's in a position to also move forward every other political and social issue mentioned in the letter.
We can all do better, but I don't think we do better when we attack others.