While the results do matter, this is probably being blown out of proportion
> One group of subjects received ibuprofen, 2 × 600 mg/d, (Ibumetin; Nycomed Denmark Aps) for a period of 6 wk
Yeah, that's a lot of Ibuprofen for a long time
> One group of subjects received ibuprofen, 2 × 600 mg/d, (Ibumetin; Nycomed Denmark Aps) for a period of 6 wk
Yeah, that's a lot of Ibuprofen for a long time
But it's not a dose people will commonly take in their "day to day" activities and ideally not something that is done without medical supervision
This makes it different to Paracetamol, where you only have to double or triple the standard dose to cause temporary liver damage, and increasing it only slightly further puts you in danger of death.
A lot of people who exercise multiple times a week take "Vitamin I" every day. So do people who have frequent headaches, back or joint pain, etc. I probably came close to these levels during a bout of plantar fasciitis, though I've since switched to naproxen in such cases. It might not be common in your immediate circle, but in the broader world it's not rare enough to raise any eyebrows.
6 weeks is a long time to be popping 1200mg/d!
I've felt compelled to say to more than one person: probably shouldn't take that much ...
Of course, there are folks who take over-the-counter meds as though it is safe at any dose and frequency. That might warrant a nudge toward reading the label about safe dosage, or a mention of a recent study on the subject.
Construction workers, manual laborers, etc.
A lot of people I know that powerlift do 4 x 800mg for 5 days or so. I think the thinking is to give the injury a "blast" of ibuprofen to bring the swelling down fast, rather than a lower dose for a longer period.