There's a parser text game called Hadean Lands in which you're on board a "spaceship" fueled by alchemy. You start the game by learning some basic rituals, then progressively you have more and more components missing for what you have to do next and have to hack together something based on concepts you learn progressively like planetary or elemental associations.
As weird as it is, everything makes perfect sense as you internalize the connections between things like planets, scents, classical elements, and other concepts. Within the world of the game, strange alchemical connections are as much a science as physics is in ours.
It's definitely a different experience to dip into that mindset, even just within a game.